公表論文/Publication

2024年

Yamamoto, S., Ogasawara, N., Sudo-Yokoyama, Y., Sato, S., Takata, N., Yokota, N., Nakano, T., Hayashi, K., Takasawa, A., Endo, M., Hinatsu, M., Yoshida, K., Sato, T., Takahashi, S., Takano, K., Kojima, T., Hiraki, J., Yokota, SI. (2024) Bacillaceae serine proteases and Streptomyces epsilon-poly-L-lysine synergistically inactivate Caliciviridae by inhibiting RNA genome release. Sci Rep, 14:15181.

Yamamoto, K., Sato, T., Hao, A., Asao, K., Kaguchi, R., Kusaka, S., Ruddarraju, RR., Kazamori, D., Seo, K., Takahashi, S., Horiuchi, M., Yokota, SI., Lee, SY., Ichikawa, S. (2024) Development of a natural product optimization strategy for inhibitors against MraY, a promising antibacterial target. Nat Commun, 15:5085.

Sasaoka, K., Sato, T., Morishita, K., Hosoya, K., Yokoyama, N., Sato, T., Horiuchi, M., Takiguchi, M. (2024) Antimicrobial resistance and self-reported hand hygiene awareness before and after an infection prevention and control programme: A 7-year analysis in a small animal veterinary teaching hospital. Vet J, 306:106154.

Bulgan, E., Byambajav, Z., Ayushjav, N., Hirai, Y., Tanaka, M., Purevdorj, NO., Badrakh, S., Suzuki, A., Komatsu, Y., Sato, T., Horiuchi M. (2024) Characterization of Shiga Toxin-producing Escherichia coli Isolated from Cattle Around Ulaanbaatar City, Mongolia. J Food Prot, 87:100294.

Sato, T., Uemura, K., Yasuda, M., Maeda, A., Minamoto, T., Harada, K., Sugiyama, M., Ikushima, S., Yokota, SI., Horiuchi, M., Takahashi, S., Asai, T. (2024) Traces of pandemic fluoroquinolone-resistant Escherichia coli clone ST131 transmitted from human society to aquatic environments and wildlife in Japan. One Health, 18:100715

Toyting, J., Nuanmuang, N., Utrarachkij, F., Supha, N., Thongpanich, Y., Leekitcharoenphon, P., Aarestrup, FM., Sato, T., Thapa, J., Nakajima, C., Suzuki, Y. (2024) Genomic analysis of Salmonella isolated from canal water in Bangkok, Thailand. Microbiol Spectr, Apr 2:e0421623.

Hiyama, Y., Yamamoto, S., Sato, T., Ogasawara, N., Masumori, N., Takahashi, S., Yokota, SI. (2024) Affinity of β-Lactam Antibiotics for Neisseria gonorrhoeae Penicillin-Binding Protein 2 Having Wild, Cefixime-Reduced-Susceptible, and Cephalosporin (Ceftriaxone)-Resistant penA Alleles. Microb Drug Resist, 30:141.

2023年

Konno, A., Okubo, T., Enoeda, Y., Uno, T., Sato, T., Yokota, SI., Yano, R., Yamaguchi, H. (2023) Human pathogenic bacteria on high-touch dry surfaces can be controlled by warming to human-skin temperature under moderate humidity. PLoS One, 18(9):e0291765.

Yokota, SI., Tsukamoto, N., Sato, T., Ohkoshi, Y., Yamamoto, S., Ogasawara, N. (2023) Serotype replacement and an increase in non-encapsulated isolates among community-acquired infections of Streptococcus pneumoniae during post-vaccine era in Japan. IJID Reg., 8:105.

Fukuzawa, S., Sato, T., Aoki, K., Yamamoto, S., Ogasawara, N., Nakajima, C., Suzuki, Y., Horiuchi, M., Takahashi, S., Yokota SI. (2923) High prevalence of colistin heteroresistance in specific species and lineages of Enterobacter cloacae complex derived from human clinical specimens. Ann Clin Microbiol Antimicrob., 22:60.

Nagano, Y., Kuronuma, K., Kitamura, Y., Nagano, K., Yabe, H., Kudo, S., Sato, T., Nirasawa, S., Nakae, M., Horiuchi, M., Yokota, SI., Fujiya, Y., Saito, A., Takahashi, S., Chiba, H. (2023) Pseudo-outbreak of Mycobacterium lentiflavum at a general hospital in Japan. Infect Control Hosp Epidemiol., 44:1809.

Fukushima, Y., Sato, T., Tsukamoto, N., Nakajima, C., Suzuki, Y., Takahashi, S., Yokota, SI. Corrigendum to 'Clonal/subclonal changes and accumulation of CTX-M-type β-lactamase genes in fluoroquinolone-resistant Escherichia coli ST131 and ST1193 strains isolated during the past 12 years, Japan' [Journal of Global Antimicrobial Resistance 27 (2021) 150-155]. (2023). J Glob Antimicrob Resist. 32:195.

Kaguchi, R., Katsuyama, A., Sato, T., Takahashi, S., Horiuchi, M., Yokota, SI., Ichikawa, S. (2023) Discovery of Biologically Optimized Polymyxin Derivatives Facilitated by Peptide Scanning and In Situ Screening Chemistry. J Am Chem Soc. 145:3665

2022年

Sato, T., Harada, K., Usui, M., Yokota, SI., Horiuchi, M.  (2022) Colistin susceptibility in companion animal-derived Escherichia coli, Klebsiella spp., and Enterobacter spp. in Japan: Frequent isolation of colistin-resistant Enterobacter cloacae complex. Front Cell Infect Microbiol, in press.

Matsuura, Y., Miyazawa, K., Horiuchi, M., Suzuki, A., Yokoyama, M., Imamura, M., Ikeda, K., Iwamaru, Y. (2022) Extended application of the rapid post-mortem test kit for bovine spongiform encephalopathy to chronic wasting disease. Microbiol Immunol.

Takashina, K., Katsuyama, A., Kaguchi, R., Yamamoto, K., Sato, T., Takahashi, S., Horiuchi, M., Yokota, S.I., Ichikawa, S. (2022) Solid-Phase Total Synthesis of Plusbacin A(3). Org Lett.

Nakaya, T., Yabe, M., Mashalidis, EH., Sato, T., Yamamoto, K., Hikiji, Y.

, Katsuyama, A., Shinohara, M., Minato, Y., Takahashi, S., Horiuchi, M., Yokota, SI., Lee, SY., Ichikawa, S. (2022) Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY. Nat Commun 13: 7575

Miyazato, Y., Iwamoto, N., Usui, M., Sato, T., Miyoshi-Akiyama, T., Nagashima, M., Mezaki, K., Hayakawa, K., Ohmagari, N. (2022) Chromosomal coharboring of blaIMP-60 and mcr-9 in Enterobacter asburiae isolated from a Japanese woman with empyema: a case report. BMC Infect Dis 22:762

Sato, T., Harada, K., Usui, M., Yokota, SI., Horiuchi, M. (2022) Colistin Susceptibility in Companion Animal-Derived Escherichia coli, Klebsiella spp., and Enterobacter spp. in Japan: Frequent Isolation of Colistin-Resistant Enterobacter cloacae Complex. Front Cell Infect Microbiol 12: 946841

Takumi-Tanimukai, Y., Yamamoto, S., Ogasawara, N., Nakabayashi, S., Mizuta, K., Yamamoto, K., Miyata, R., Kakuki, T., Jitsukawa, S., Sato, T.

, Tsutsumi, H., Kojima, T., Takano, K., Yokota, SI. (2022) A hydroxypropyl methylcellulose plaque assay for human respiratory syncytial virus. J Virol Methods 204: 114528

Yokota, K., Osaki, T., Hayashi, S., Yokota, SI., Takeuchi, H., Rimbara, E., Ojima, H., Sato, T., Yonezawa, H., Shibayama, K., Tokunaga, K., Kamiya, S., Murakami, K., Kato, M., Sugiyama, T. (2022) Establishment of a reference panel of Helicobacter pylori strains for antimicrobial susceptibility testing. Helicobacter 27: e12874

2021年

Sato, T., Yokota, S.I., Tachibana, T., Tamai, S., Maetani, S., Tamura, Y., Horiuchi, M. (2021) Isolation of Human Lineage, Fluoroquinolone-Resistant and Extended-β-Lactamase-Producing Escherichia coli Isolates from Companion Animals in Japan. Antibiotics (Basel), 10.

Byambajav, Z., Bulgan, E., Hirai, Y., Nakayama, M., Tanaka, M., Nitta, Y., Suzuki, A., Umemura, T., Altankhuu, B., Tsagaan, A., Vanaabaatar, B., Janchivdorj, E., Purevdorj, N.O., Ayushjav, N., Yamasaki, T., Horiuchi, M. (2021) Research Note: Antimicrobial resistance of Campylobacter species isolated from chickens near Ulaanbaatar city, Mongolia. Poult Sci, 100: 100916.

Suzuki, A., Sawada, K., Erdenebat, T., Yamasaki, T., Tobiume, M., Suga, K., Horiuchi, M. (2021) Monitoring of chronic wasting disease using real-time quaking-induced conversion assay in Japan. J Vet Med Sci, 83: 1735-1739.

Imoto, D., Yamamoto, I., Matsunaga, H., Yonekura, T., Lee, M.L., Kato, K.X., Yamasaki, T., Xu, S., Ishimoto, T., Yamagata, S., Otsuguro, K.I., Horiuchi, M., Iijima, N., Kimura, K., Toda, C. (2021) Refeeding activates neurons in the dorsomedial hypothalamus to inhibit food intake and promote positive valence. Mol Metab, 54: 101366.

Sandagdorj, B., Baigalmaa, T., Burenjargal, S., Horiuchi, M., Enkhdalai, M., Bayanbat, D., Janchiv, D., Jamyandorj, O., Ulzii-Orshikh, P., Nyam-Osor, P. (2021) Relationship between lactational performance and metabolic parameters of Mongolian native grazing mares. J Equine Sci, 32: 91-98.

2020年

Sakaguchi, S., Shintani, S., Kamio, K., Sekiya, A., Kato, S., Muroi, Y., Horiuchi, M., Furuoka, H. (2020) Selective neuronal vulnerability is involved in cerebellar lesions of Guinea pigs infected with bovine spongiform encephalopathy (BSE) prions: Immunohistochemical and electron microscopic investigations. Neuropathology, 40: 167-179.

Suzuki, A., Sawada, K., Yamasaki, T., Denkers, N.D., Mathiason, C.K., Hoover, E.A., Horiuchi, M. (2020) Involvement of N- and C-terminal region of recombinant cervid prion protein in its reactivity to CWD and atypical BSE prions in real-time quaking-induced conversion reaction in the presence of high concentrations of tissue homogenates. Prion, 14: 283-295.

Tanaka, M., Yamasaki, T., Hasebe, R., Suzuki, A., Horiuchi, M. (2020) Enhanced phosphorylation of PERK in primary cultured neurons as an autonomous neuronal response to prion infection. PLoS One, 15: e0234147.

2019年

Temuujin, U., Tserendorj, A., Fujiki, J., Sakoda, Y., Tseren-Ochir, E.O., Okamatsu, M., Matsuno, K., Sharav, T., Horiuchi, M., Umemura, T., Chultemdorj, T. (2019) The first isolation and identification of canine parvovirus (CPV) type 2c variants during 2016-2018 genetic surveillance of dogs in Mongolia. Infect Genet Evol, 73: 269-275.

Hagiwara, K., Sato, Y., Yamakawa, Y., Hara, H., Tobiume, M., Okemoto-Nakamura, Y., Sata, T., Horiuchi, M., Shibata, H., Ono, F. (2019) Tracking and clarifying differential traits of classical- and atypical L-type bovine spongiform encephalopathy prions after transmission from cattle to cynomolgus monkeys. PLoS One, 14: e0216807.

Suzuki, A., Yamasaki, T., Hasebe, R., Horiuchi, M. (2019) Enhancement of binding avidity by bivalent binding enables PrPSc-specific detection by anti-PrP monoclonal antibody 132. PLoS One, 14: e0217944.

Muramatsu, Y., Haraya, N., Horie, K., Uchida, L., Kooriyama, T., Suzuki, A., Horiuchi, M. (2019) Bergeyella zoohelcum isolated from oral cavities of therapy dogs. Zoonoses Public Health, 66: 936-942.

Sawada, K., Suzuki, A., Yamasaki, T., Iwamaru, Y., Matsuura, Y., Miyazawa, K., Masujin, K., Atarashi, R., Horiuchi, M. (2019) Estimation of prion infectivity in tissues of cattle infected with atypical BSE by real time-quaking induced conversion assay. J Vet Med Sci, 81: 846-850.

2018年

Yamasaki, T., Suzuki, A., Hasebe, R., Horiuchi, M. (2018a) Flow Cytometric Detection of PrP(Sc) in Neurons and Glial Cells from Prion-Infected Mouse Brains. J Virol, 92.

Yamasaki, T., Suzuki, A., Hasebe, R., Horiuchi, M. (2018b) Retrograde Transport by Clathrin-Coated Vesicles is Involved in Intracellular Transport of PrP(Sc) in Persistently Prion-Infected Cells. Sci Rep, 8: 12241.

2017年

Hasebe, R., Nakao, R., Ohnuma, A., Yamasaki, T., Sawa, H., Takai, S., Horiuchi, M. (2017) Listeria monocytogenes serotype 4b strains replicate in monocytes/macrophages more than the other serotypes. J Vet Med Sci, 79: 962-969.

Shan, Z., Hirai, Y., Nakayama, M., Hayashi, R., Yamasaki, T., Hasebe, R., Song, C.H., Horiuchi, M. (2017) Therapeutic effect of autologous compact bone-derived mesenchymal stem cell transplantation on prion disease. J Gen Virol, 98: 2615-2627.

2016年

Hasebe, R., Tanaka, M., Suzuki, A., Yamasaki, T., Horiuchi, M. (2016) Complement factors alter the amount of PrP(Sc) in primary-cultured mouse cortical neurons associated with increased membrane permeability. Virology, 496: 9-20.

Tanaka, M., Fujiwara, A., Suzuki, A., Yamasaki, T., Hasebe, R., Masujin, K., Horiuchi, M. (2016) Comparison of abnormal isoform of prion protein in prion-infected cell lines and primary-cultured neurons by PrPSc-specific immunostaining. J Gen Virol, 97: 2030-2042.

Saijo, E., Hughson, A.G., Raymond, G.J., Suzuki, A., Horiuchi, M., Caughey, B. (2016) PrPSc-Specific Antibody Reveals C-Terminal Conformational Differences between Prion Strains. J Virol, 90: 4905-4913.

Shan, Z., Yamasaki, T., Suzuki, A., Hasebe, R., Horiuchi, M. (2016) Establishment of a simple cell-based ELISA for the direct detection of abnormal isoform of prion protein from prion-infected cells without cell lysis and proteinase K treatment. Prion, 10: 305-318.

2015年

Nagasawa, Y., Takahashi, Y., Itani, W., Watanabe, H., Hidaka, Y., Morita, S., Watanabe, K., Ohwada, S., Kitazawa, H., Imamura, M., Yokoyama, T., Horiuchi, M., Sakaguchi, S., Mohri, S., Rose, M., Nochi, T., Aso, H. (2015) Prion protein binds to aldolase A of bovine intestinal M cells. Open Journal of Veterinary Medicine; 05(03):43-60,.

2014年

Yamasaki, T., Baron, G.S., Suzuki, A., Hasebe, R., Horiuchi, M. (2014a) Characterization of intracellular dynamics of inoculated PrP-res and newly generated PrP(Sc) during early stage prion infection in Neuro2a cells. Virology, 450-451: 324-335.

Yamasaki, T., Suzuki, A., Hasebe, R., Horiuchi, M. (2014b) Comparison of the anti-prion mechanism of four different anti-prion compounds, anti-PrP monoclonal antibody 44B1, pentosan polysulfate, chlorpromazine, and U18666A, in prion-infected mouse neuroblastoma cells. PLoS One, 9: e106516.

Hasebe, R., Suzuki, A., Yamasaki, T., Horiuchi, M. (2014) Temporary upregulation of anti-inflammatory cytokine IL-13 expression in the brains of CD14 deficient mice in the early stage of prion infection. Biochem Biophys Res Commun, 454: 125-130.

2013年

Ohsawa, N., Song, C.H., Suzuki, A., Furuoka, H., Hasebe, R., Horiuchi, M. (2013) Therapeutic effect of peripheral administration of an anti-prion protein antibody on mice infected with prions. Microbiol Immunol, 57: 288-297.

Sakai, K., Hasebe, R., Takahashi, Y., Song, C.H., Suzuki, A., Yamasaki, T., Horiuchi, M. (2013) Absence of CD14 delays progression of prion diseases accompanied by increased microglial activation. J Virol, 87: 13433-13445.

2012年

Yoshikawa, Y., Horiuchi, M., Ishiguro, N., Kadohira, M., Kai, S., Mizusawa, H., Nagata, C., Onodera, T., Sata, T., Tsutsui, T., Yamada, M., Yamamoto, S. (2012) Alternative BSE risk assessment methodology for beef and beef offal imported into Japan. J Vet Med Sci, 74: 959-968.

Yamasaki, T., Suzuki, A., Shimizu, T., Watarai, M., Hasebe, R., Horiuchi, M. (2012) Characterization of intracellular localization of PrP(Sc) in prion-infected cells using a mAb that recognizes the region consisting of aa 119-127 of mouse PrP. J Gen Virol, 93: 668-680.

Hasebe, R., Raymond, G.J., Horiuchi, M., Caughey, B. (2012) Reaction of complement factors varies with prion strains in vitro and in vivo. Virology, 423: 205-213.

Nakato, G., Hase, K., Suzuki, M., Kimura, M., Ato, M., Hanazato, M., Tobiume, M., Horiuchi, M., Atarashi, R., Nishida, N., Watarai, M., Imaoka, K., Ohno, H. (2012) Cutting Edge: Brucella abortus exploits a cellular prion protein on intestinal M cells as an invasive receptor. J Immunol, 189: 1540-1544.

2011年

Sassa, Y., Yamamoto, H., Mochizuki, M., Umemura, T., Horiuchi, M., Ishiguro, N., Miyazawa, T. (2011) Successive deaths of a captive snow leopard (Uncia uncia) and a serval (Leptailurus serval) by infection with feline panleukopenia virus at Sapporo Maruyama Zoo. J Vet Med Sci, 73: 491-494.

Song, C.H., Honmou, O., Furuoka, H., Horiuchi, M. (2011) Identification of chemoattractive factors involved in the migration of bone marrow-derived mesenchymal stem cells to brain lesions caused by prions. J Virol, 85: 11069-11078.

2010年

Watanabe, Y., Hiraoka, W., Igarashi, M., Ito, K., Shimoyama, Y., Horiuchi, M., Yamamori, T., Yasui, H., Kuwabara, M., Inagaki, F., Inanami, O. (2010) A novel copper(II) coordination at His186 in full-length murine prion protein. Biochem Biophys Res Commun, 394: 522-528.

Hasebe, R., Suzuki, T., Makino, Y., Igarashi, M., Yamanouchi, S., Maeda, A., Horiuchi, M., Sawa, H., Kimura, T. (2010) Transcellular transport of West Nile virus-like particles across human endothelial cells depends on residues 156 and 159 of envelope protein. BMC Microbiol, 10: 165.

Nakamitsu, S., Kurokawa, A., Yamasaki, T., Uryu, M., Hasebe, R., Horiuchi, M. (2010) Cell density-dependent increase in the level of protease-resistant prion protein in prion-infected Neuro2a mouse neuroblastoma cells. J Gen Virol, 91: 563-569.

Sakata, H., Horiuchi, M., Takahashi, I., Kinjo, M. (2010) Confomational analysis of soluble oligomers of GFP tagged prion protein by fluorescence fluctuation spectroscopy. Curr Pharm Biotechnol, 11: 87-95.

Sassa, Y., Yamasaki, T., Horiuchi, M., Inoshima, Y., Ishiguro, N. (2010) The effects of lysosomal and proteasomal inhibitors on abnormal forms of prion protein degradation in murine macrophages. Microbiol Immunol, 54: 763-768.

Sato, Y., Shimonohara, N., Hanaki, K., Goto, M., Yamakawa, Y., Horiuchi, M., Takahashi, H., Sata, T., Nakajima, N. (2010) ImmunoAT method: An initial assessment for the detection of abnormal isoforms of prion protein in formalin-fixed and paraffin-embedded tissues. J Virol Methods, 165: 261-267.

2009年以前（主要なpublication）

Horiuchi, M., Karino, A., Furuoka, H., Ishiguro, N., Kimura, K., Shinagawa, M. (2009) Generation of monoclonal antibody that distinguishes PrPSc from PrPC and neutralizes prion infectivity. Virology, 394: 200-207.

Song, C.H., Honmou, O., Ohsawa, N., Nakamura, K., Hamada, H., Furuoka, H., Hasebe, R., Horiuchi, M. (2009) Effect of transplantation of bone marrow-derived mesenchymal stem cells on mice infected with prions. J Virol, 83: 5918-5927.

Shindoh, R., Kim, C.L., Song, C.H., Hasebe, R., Horiuchi, M. (2009) The region approximately between amino acids 81 and 137 of proteinase K-resistant PrPSc is critical for the infectivity of the Chandler prion strain. J Virol, 83: 3852-3860.

Song, C.H., Furuoka, H., Kim, C.L., Ogino, M., Suzuki, A., Hasebe, R., Horiuchi, M. (2008) Effect of intraventricular infusion of anti-prion protein monoclonal antibodies on disease progression in prion-infected mice. J Gen Virol, 89: 1533-1544.

Fujii, F., Horiuchi, M., Ueno, M., Sakata, H., Nagao, I., Tamura, M., Kinjo, M. (2007) Detection of prion protein immune complex for bovine spongiform encephalopathy diagnosis using fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy. Anal Biochem, 370: 131-141.

Uryu, M., Karino, A., Kamihara, Y., Horiuchi, M. (2007) Characterization of prion susceptibility in Neuro2a mouse neuroblastoma cell subclones. Microbiol Immunol, 51: 661-669.

Iwata, N., Sato, Y., Higuchi, Y., Nohtomi, K., Nagata, N., Hasegawa, H., Tobiume, M., Nakamura, Y., Hagiwara, K., Furuoka, H., Horiuchi, M., Yamakawa, Y., Sata, T. (2006) Distribution of PrP(Sc) in cattle with bovine spongiform encephalopathy slaughtered at abattoirs in Japan. Jpn J Infect Dis, 59: 100-107.

Horiuchi, M., Furuoka, H., Kitamura, N., Shinagawa, M. (2006) Alymphoplasia mice are resistant to prion infection via oral route. Jpn J Vet Res, 53: 149-157.

Furuoka, H., Yabuzoe, A., Horiuchi, M., Tagawa, Y., Yokoyama, T., Yamakawa, Y., Shinagawa, M., Sata, T. (2005) Effective antigen-retrieval method for immunohistochemical detection of abnormal isoform of prion proteins in animals. Acta Neuropathol, 109: 263-271.

Kim, C.L., Karino, A., Ishiguro, N., Shinagawa, M., Sato, M., Horiuchi, M. (2004a) Cell-surface retention of PrPC by anti-PrP antibody prevents protease-resistant PrP formation. J Gen Virol, 85: 3473-3482.

Kim, C.L., Umetani, A., Matsui, T., Ishiguro, N., Shinagawa, M., Horiuchi, M. (2004b) Antigenic characterization of an abnormal isoform of prion protein using a new diverse panel of monoclonal antibodies. Virology, 320: 40-51.

Watarai, M., Kim, S., Erdenebaatar, J., Makino, S., Horiuchi, M., Shirahata, T., Sakaguchi, S., Katamine, S. (2003) Cellular prion protein promotes Brucella infection into macrophages. J Exp Med, 198: 5-17.

Horiuchi, M., Nemoto, T., Ishiguro, N., Furuoka, H., Mohri, S., Shinagawa, M. (2002) Biological and biochemical characterization of sheep scrapie in Japan. J Clin Microbiol, 40: 3421-3426.

Wong, C., Xiong, L.W., Horiuchi, M., Raymond, L., Wehrly, K., Chesebro, B., Caughey, B. (2001) Sulfated glycans and elevated temperature stimulate PrP(Sc)-dependent cell-free formation of protease-resistant prion protein. EMBO J, 20: 377-386.

Horiuchi, M., Baron, G.S., Xiong, L.W., Caughey, B. (2001) Inhibition of interactions and interconversions of prion protein isoforms by peptide fragments from the C-terminal folded domain. J Biol Chem, 276: 15489-15497.

Horiuchi, M., Priola, S.A., Chabry, J., Caughey, B. (2000) Interactions between heterologous forms of prion protein: binding, inhibition of conversion, and species barriers. Proc Natl Acad Sci U S A, 97: 5836-5841.

Horiuchi, M., Caughey, B. (1999a) Prion protein interconversions and the transmissible spongiform encephalopathies. Structure, 7: R231-240.

Horiuchi, M., Caughey, B. (1999b) Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state. EMBO J, 18: 3193-3203.

Caughey, B., Horiuchi, M., Demaimay, R., Raymond, G.J. (1999) Assays of protease-resistant prion protein and its formation. Methods Enzymol, 309: 122-133.

Caughey, W.S., Raymond, L.D., Horiuchi, M., Caughey, B. (1998) Inhibition of protease-resistant prion protein formation by porphyrins and phthalocyanines. Proc Natl Acad Sci U S A, 95: 12117-12122.

Horiuchi, M., Yamaguchi, Y., Gojobori, T., Mochizuki, M., Nagasawa, H., Toyoda, Y., Ishiguro, N., Shinagawa, M. (1998) Differences in the evolutionary pattern of feline panleukopenia virus and canine parvovirus. Virology, 249: 440-452.

Horiuchi, M., Mochizuki, M., Ishiguro, N., Nagasawa, H., Shinagawa, M. (1997b) Epitope mapping of a monoclonal antibody specific to feline panleukopenia virus and mink enteritis virus. J Vet Med Sci, 59: 133-136.

Grathwohl, K.U., Horiuchi, M., Ishiguro, N., Shinagawa, M. (1997) Sensitive enzyme-linked immunosorbent assay for detection of PrP(Sc) in crude tissue extracts from scrapie-affected mice. J Virol Methods, 64: 205-216.

Mochizuki, M., Horiuchi, M., Hiragi, H., San Gabriel, M.C., Yasuda, N., Uno, T. (1996) Isolation of canine parvovirus from a cat manifesting clinical signs of feline panleukopenia. J Clin Microbiol, 34: 2101-2105.

Horiuchi, M., Yamazaki, N., Ikeda, T., Ishiguro, N., Shinagawa, M. (1995) A cellular form of prion protein (PrPC) exists in many non-neuronal tissues of sheep. J Gen Virol, 76 ( Pt 10): 2583-2587.

Ikeda, T., Horiuchi, M., Ishiguro, N., Muramatsu, Y., Kai-Uwe, G.D., Shinagawa, M. (1995) Amino acid polymorphisms of PrP with reference to onset of scrapie in Suffolk and Corriedale sheep in Japan. J Gen Virol, 76 ( Pt 10): 2577-2581.

Horiuchi, M., Goto, H., Ishiguro, N., Shinagawa, M. (1994) Mapping of determinants of the host range for canine cells in the genome of canine parvovirus using canine parvovirus/mink enteritis virus chimeric viruses. J Gen Virol, 75 ( Pt 6): 1319-1328.

Horiuchi, M., Ishiguro, N., Goto, H., Shinagawa, M. (1992) Characterization of the stage(s) in the virus replication cycle at which the host-cell specificity of the feline parvovirus subgroup is regulated in canine cells. Virology, 189: 600-608.